Too often, traditional methods for assessing risk of coronary heart disease in asymptomatic patients wrongly identify some healthy individuals as high risk, while missing impending problems in others. Overtreatment can mean unnecessary costs and increased anxiety for those diagnosed, while undertreatment can lead to myocardial infarctions and death. Researchers have therefore begun to examine nontraditional markers in hopes of finding more accurate screening tools.
Mitka M. Task Force: Nontraditional Markers Add Little to Heart Risk Assessment. JAMA. 2009;302(20):2192-2193. doi:10.1001/jama.2009.1678