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Clinical Trials Update
March 26, 2014

Testosterone Therapy Boosts MI Risk

JAMA. 2014;311(12):1191. doi:10.1001/jama.2014.3044

Men treated with testosterone therapy (TT) are at substantially increased risk of acute nonfatal myocardial infarction (MI), concluded authors of a cohort study of 55 593 men (Finkle W et al. PLoS One. doi:10.1371/journal.pone.0085805 [published online January 29, 2014]).

Men aged 65 years and older doubled their risk of MI within 3 months of filling an initial TT prescription. Younger men with a history of heart disease doubled or tripled their risk of MI within 90 days, but risk did not increase in younger men without heart disease.

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