Men treated with testosterone therapy (TT) are at substantially increased risk of acute nonfatal myocardial infarction (MI), concluded authors of a cohort study of 55 593 men (Finkle W et al. PLoS One. doi:10.1371/journal.pone.0085805 [published online January 29, 2014]).
Men aged 65 years and older doubled their risk of MI within 3 months of filling an initial TT prescription. Younger men with a history of heart disease doubled or tripled their risk of MI within 90 days, but risk did not increase in younger men without heart disease.
Slomski A. Testosterone Therapy Boosts MI Risk. JAMA. 2014;311(12):1191. doi:10.1001/jama.2014.3044