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January 13, 2010

Intervention Timing and Acute Coronary Syndromes

JAMA. 2010;303(2):131-132. doi:10.1001/jama.2009.1968

To the Editor: The report of the ABOARD trial by Dr Montalescot and colleagues1 provided important information on the feasibility of an early invasive diagnostic strategy in patients with non–ST-segment elevation acute coronary syndromes (NSTE-ACS). However, the influence of timing of the therapeutic intervention, especially percutaneous coronary intervention (PCI), might be more subtle than ABOARD could evaluate. In ABOARD, only 222 of 352 patients (63%) were treated with PCI. Because of a wide diversity in patient characteristics, such as time from onset of pain and treatment modalities, firm conclusions cannot be drawn for PCI use.

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