In Reply Therapeutic hypothermia always includes an induction phase and a maintenance phase.1 In our study, induction was obtained by infusion of cold saline. This technique was proven to be safe in several types of cerebral injuries.2 Because all centers did not use the same hypothermia technique, we tried to obtain a uniform and quick induction phase in the hypothermia group.
Mourvillier B, Wolff M. Hypothermia for Bacterial Meningitis—Reply. JAMA. 2014;311(13):1358. doi:10.1001/jama.2014.1478