In Reply: We appreciate Dr Lockshin and colleagues clarifying their journals' editorial policy regarding trial registration. However, in our study the designation of journal status regarding trial registration policy (whether registration was required) was based only on the instructions for authors, since most authors usually refer to this guidance for a journal's policy. We did not consider other methods used to enforce trial registration, such as publication of an editorial or specific action during the review process.
Mathieu S, Boutron I, Ravaud P. Clinical Trial Registration and Publication of Randomized Controlled Trials—Reply. JAMA. 2010;303(6):517-518. doi:10.1001/jama.2010.96