In Reply: We agree with Dr Lewin and colleagues that CBTs are often safe and effective alternatives or adjuncts to atypical antipsychotic medications for nonpsychotic psychiatric syndromes in children and adolescents. Cognitive behavioral therapies have demonstrated efficacy for pediatric depression, OCD, anxiety, and posttraumatic stress disorder.1 Parent training programs are effective for children with behavioral problems.2 Recent studies support the benefit of CBT-based therapies for pediatric bipolar disorder3 and developmentally tailored behavioral interventions for autistic spectrum disorder,4 conditions for which there are US Food and Drug Administration indications for atypical antipsychotic medications.
Varley C, McClellan J. Risks From Antipsychotic Medications in Children and Adolescents—Reply. JAMA. 2010;303(8):729-731. doi:10.1001/jama.2010.134