Scientists have long been stymied in their efforts to develop effective treatments for glioblastoma multiforme, a rapidly growing cancer of the brain that patients rarely survive much longer than a year. But a flurry of recent studies exploring the genomics of the disorder offer clues about why this cancer is so aggressive, help to classify patients and their response to existing therapies, and provide much-needed new targets for experimental therapies.
Kuehn BM. Genomics Illuminates a Deadly Brain Cancer. JAMA. 2010;303(10):925-927. doi:10.1001/jama.2010.236