Could it be that the revolution in molecular biology that took place over the last several decades actually set back clinical oncology, rather than advancing it? Tak Mak, PhD, director of the Campbell Family Institute for Breast Cancer Research, in Toronto, Ontario, Canada, poses this provocative question—not to criticize cancer genetics research, in which he is involved, but rather to call attention to the fact that it may have obscured earlier insights into the role that cancer cells' altered metabolism plays in tumor development and growth.
Friedrich MJ. Researchers Aim to Stop Tumor Growth by Shutting Off Cancer’s Fuel Supply. JAMA. 2010;303(11):1021-1022. doi:10.1001/jama.2010.270