A genome-wide association study by US researchers has led to the discovery of the first major gene site responsible for the severe food allergy eosinophilic esophagitis (EoE), a disorder that features the accumulation of eosinophils in the esophagus (Rothenberg ME et al. Nat Genet. doi:10.1038/ng.547 [published online ahead of print March 7, 2010]). EoE may cause weight loss, vomiting, heartburn, and swallowing difficulties in affected individuals.
Hampton T. Clues to Food Allergy. JAMA. 2010;303(13):1245. doi:10.1001/jama.2010.348