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Book and Media Reviews
April 21, 2010

Pediatric Oncology Nursing: Advanced Clinical Handbook

JAMA. 2010;303(15):1541-1544. doi:10.1001/jama.2010.466

Pediatric Oncology Nursing: Advanced Clinical Handbook is the resource every advanced practice hematology/oncology nurse, whether nurse practitioner or clinical specialist, should own. It delivers a thorough, well-organized, succinct discussion of childhood cancers and hematologic disorders. The book is jointly written and edited by representatives from Canada, the United Kingdom, and the United States, thus providing comprehensive and cutting-edge clinical practice and research information. For most of the conditions, a “Future Perspectives” section highlights the status of promising new therapeutic strategies specific to a given condition. These include modifying dosing of antileukemic drugs according to a child's inherited metabolic processes, use of gene-expression profiling and biological agents plus targeting abnormal transduction pathways to treat a child's primary or relapsed neuroblastoma, various gene manipulation studies including retroviral vectors that could correct the mutation causing sickle cell disease, and other potential discoveries on the horizon.

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