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April 9, 2014

From JAMA’s Daily News Site

Author Affiliations

Copyright 2014 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.

JAMA. 2014;311(14):1388. doi:10.1001/jama.2014.3150

New hope may be on the horizon for children with potentially fatal severe peanut allergy.

Two recent studies examined oral immunotherapy use in children allergic to peanuts. In the first, researchers randomly assigned 99 children to receive either 6 months of oral immunotherapy or no treatment. Of 39 children who completed the treatment, 24 (62%) were successfully desensitized compared with none in the control group. In the second study, 43 patients were randomly assigned to receive 24 months of oral immunotherapy or no therapy. Of 23 patients given oral immunotherapy, 20 became desensitized, but only 7 remained so after 3 months.

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