[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address 54.204.247.205. Please contact the publisher to request reinstatement.
[Skip to Content Landing]
Citations 0
Letters
April 28, 2010

Depression Severity and Effect of Antidepressant Medications

JAMA. 2010;303(16):1596-1599. doi:10.1001/jama.2010.506

To the Editor: The meta-analysis of antidepressants by Mr Fournier and colleagues1 is important for clinical practice, but I have 3 reservations. First, although the authors had access to individual patient data, they used last observation carried forward for patients who dropped out. This method of imputation is likely to overestimate the effect of antidepressants.2

First Page Preview View Large
First page PDF preview
First page PDF preview
×