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Letters
May 12, 2010

Antiarrhythmic Drug Therapy vs Catheter Ablation for Paroxysmal Atrial Fibrillation

JAMA. 2010;303(18):1808-1810. doi:10.1001/jama.2010.536

To the Editor: In their randomized controlled trial, Dr Wilber and colleagues1 concluded that catheter ablation was superior to antiarrhythmic drug therapy (ADT) in patients with paroxysmal atrial fibrillation (AF) refractory to at least 1 antiarrhythmic drug. However, because of the study design it is possible that the effect of ADT might have been underestimated.

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