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May 12, 2010

Antiarrhythmic Drug Therapy vs Catheter Ablation for Paroxysmal Atrial Fibrillation

JAMA. 2010;303(18):1808-1810. doi:10.1001/jama.2010.539

To the Editor: In their trial comparing catheter ablation and ADT, Dr Wilber and colleagues1 showed that the primary end point of treatment failure was higher in the ADT group. Thirteen patients (12.6%) in the catheter ablation group required repeat ablation within 80 days. It is not clear whether the adverse effects reported in the catheter ablation group included those following repeat procedures, or how many patients needed repeat ablation after the first 80 days.

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