To the Editor: Dr Hemmelgarn and colleagues1 analyzed the relationship between kidney function and proteinuria and the risks of mortality, myocardial infarction, and progression to kidney failure using a community-based cohort study with 920 985 adults. They pointed out the problem of the current staging of chronic kidney disease (CKD) without consideration of the severity of proteinuria.
Nonoguchi H, Nanami M, Nakanishi T. Kidney Function, Proteinuria, and Adverse Outcomes. JAMA. 2010;303(20):2030. doi:10.1001/jama.2010.656