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Medical News & Perspectives
June 2, 2010

IOM Report Calls for a More Streamlined, Faster Cancer Cooperative Trials Program

JAMA. 2010;303(21):2126-2127. doi:10.1001/jama.2010.695

A new report from the Institute of Medicine (IOM) calls foran overhaul of the National Cancer Institute's (NCI’s) Cooperative Group to boost efficiency and allow more complex study designs.

The Cooperative Group Program is credited with substantially improving cancer treatments by conducting large practice-changing clinical trials that would not be undertaken by private sponsors. But the IOM report, which was commissioned by the NCI, said the program is reaching a “state of crisis,” with a cumbersome structure, poor reimbursement for trials, and other factors hampering the program's ability to adapt to advances in science.

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