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To the Editor Dr Chen and colleagues1 evaluated the role of low-dose dopamine and nesiritide as individual strategies in treating patients with acute decongested heart failure while attempting to preserve or improve renal function. The trial found no benefit from low-dose dopamine or nesiritide with standard diuretic therapy. Despite significant advances in understanding the pathophysiology of acute heart failure, contemporary therapies have failed to have an effect.2
Kumar S. Dopamine vs Nesiritide for Acute Heart Failure With Renal Dysfunction. JAMA. 2014;311(15):1565. doi:10.1001/jama.2014.2459