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Lab Reports
July 7, 2010

Schizophrenia Therapies

JAMA. 2010;304(1):32. doi:10.1001/jama.2010.866

A new study in the roundworm Caenorhabditis elegans shows that all major classes of antipsychotic drugs used to treat schizophrenia increase signaling in the Akt signaling pathway. This pathway involves a protein family that plays a role in regulating such key cellular processes as transcription, cell growth, and apoptosis (Weeks KR et al. ACS Chem Neurosci. doi:10.1021/cn100010p [published online March 25, 2010]).

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