Even as the research community has drawn criticism for frequently overlooking women in clinical studies, one historic initiative focusing solely on women for the past 15 years has gathered an abundance of biomedical and psychosocial data related to the effects of HIV in infected females. The resulting data set has fueled hundreds of published analyses, examining such topics as factors in treatment adherence and links between mental health and survival in HIV-infected women.
The Women's Interagency HIV Study (WIHS, pronounced “wise”) is the largest prospective multicenter cohort study of HIV-positive and at-risk HIV-negative women in the United States (http://statepiaps.jhsph.edu/wihs/). It also is reportedly the longest ongoing disease progression study of HIV infection in women.
Hampton T. HIV Study Shines Spotlight on Women. JAMA. 2010;304(3):257-258. doi:10.1001/jama.2010.961