To the Editor: The study by Dr Boppana and colleagues1 conducted newborn screening for congenital cytomegalovirus (CMV) infection and found dried blood spots (DBS) to have a testing sensitivity of 28% to 34%. We believe that the authors' conclusion that DBS PCR assays are not suitable for screening newborns for congenital CMV infection is premature.
Dollard SC, Schleiss MR. Screening Newborns for Congenital Cytomegalovirus Infection. JAMA. 2010;304(4):407-408. doi:10.1001/jama.2010.1024