[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address 54.205.150.215. Please contact the publisher to request reinstatement.
[Skip to Content Landing]
Citations 0
Letters
August 18, 2010

Coronary Artery Calcium Score and Cardiovascular Event Prediction

JAMA. 2010;304(7):741-742. doi:10.1001/jama.2010.1143

To the Editor: Dr Polonsky and colleagues1 demonstrated that CACS significantly improved classification of future coronary heart disease (CHD) risk when added to traditional risk factors. It would be helpful if the authors report further how they actually used CACS to reclassify risk. It appears that they used the ln(CAC + 1) value to increase the 5-year predicted risk in model 2; however, it is less clear how risk was reclassified downwards on the basis of CACS. Knowledge of the mechanism by which they used CACS to reclassify risk will facilitate future comparative studies and provide a foundation for a potential randomized controlled trial.

First Page Preview View Large
First page PDF preview
First page PDF preview
×