Despite limited data on efficacy, percutaneous heart valve replacement (PHV) appears to be feasible option for patients who are not candidates for surgical aortic valve replacement, according to a review funded by the Agency for Health Care Research and Quality.
Remy R. Coeytaux, MD, PhD, of the Duke Clinical Research Institute and colleagues reviewed 76 case studies and series involving 2375 patients who underwent PHV via a catheter or transcatheter (Coeytaux RR et a. Ann Intern Med. 2010;153). They found a 94% success rate overall with 89% of patients surviving for 30 days. However, data on longer-term outcomes were limited. So far, the authors note, such studies have involved patients who would not be candidates for the surgical version of the procedure.
Kuehn BM. Heart Valve Replacement. JAMA. 2010;304(12):1317. doi:10.1001/jama.2010.1335