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Medical News and Perspectives
December 15, 2010

Scientists Probe Herpes in Neonates, C difficile Acquisition in Children

JAMA. 2010;304(23):2576-2577. doi:10.1001/jama.2010.1738

Findings regarding prevention and treatment of herpes simplex infection in neonates suggest shifts in current strategies, while a recent study of Clostridium difficile in children suggests an unexpected risk factor for acquiring the infection. The studies were presented at the Infectious Diseases Society of America (IDSA) meeting in October.

A current strategy for preventing transmission of herpes simplex from mother to child may not always be effective, suggest findings from a multicenter case study of 7 neonates who developed herpes infection despite maternal antiretroviral suppressive therapy. The participating centers were the Children's Hospital at Saint Peter's University Hospital in New Brunswick, NJ; the University of Texas Health Science Center at San Antonio; and the Maine Medical Center in Portland.

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