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February 25, 1998

Are the Epidemiology and Microbiology of Methicillin-Resistant Staphylococcus aureus Changing?

Author Affiliations

From the Division of Infectious Diseases, Miriam Hospital and Brown University, Providence, RI.

JAMA. 1998;279(8):623-624. doi:10.1001/jama.279.8.623

Strains of methicillin-resistant Staphylococcus aureus (MRSA) have emerged as important pathogens over the last 20 years, affecting primarily hospitalized patients.1,2 Risk factors associated with acquiring MRSA in hospitals include prolonged hospitalization, receiving care in an intensive care unit, preceding antimicrobial therapy, surgical procedures, and proximity to another patient known to be colonized or infected with MRSA.1,2 Typically, hospital-acquired strains of MRSA are multidrug resistant, ie, resistant to β-lactam agents, to erythromycin and clindamycin, and frequently to gentamicin and ciprofloxacin.2

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