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News From the Centers for Disease Control and Prevention
May 21, 2014

LCMV Implicated in Illness Among Organ Transplant Recipients

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Copyright American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.

JAMA. 2014;311(19):1959. doi:10.1001/jama.2014.4818

For the fifth time in the past decade, infection with lymphocytic choriomeningitis virus (LCMV) was implicated last year in a cluster of organ transplant recipients in Iowa who became ill.

Four patients had received organs or tissues from a 49-year-old man who died of an intracerebral hemorrhage. He had spent a lot of time outdoors along the Mississippi River, but investigators weren’t certain if he was exposed to rodents. Lymphocytic choriomeningitis virus is a rodent-borne virus that usually causes nonfatal, influenza-like illness and occasional aseptic meningitis. However, LCMV infection can be fatal if transmitted in utero or through organ transplantation (Schafer IJ et al. MMWR Morb Mortal Wkly Rep. 2014;63[11]:249).

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