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March 4, 1998

Paul Cloeren MacDonald, MD

Author Affiliations

Edited by Roxanne K. Young, Associate Editor.

JAMA. 1998;279(9):719. doi:10.1001/jama.279.9.719

Paul Cloeren MacDonald, MD, 67, professor of obstetrics and gynecology at the University of Texas Southwestern Medical Center, Dallas, died November 25, 1997, of disseminated carcinoma. He held the Cecil H. and Ida Green Distinguished Chair in Reproductive Biology and was director of the Cecil H. and Ida Green Center for Reproductive Biology Sciences.

Dr MacDonald was born in Oklahoma and his family moved to Texas during his early years. After graduation from Southern Methodist University and Southwestern Medical School in Dallas, he completed his internship in 1956 at Methodist Hospital of Dallas and then served in the US Navy for 2 years. He returned to Dallas for residency training in obstetrics and gynecology at Parkland Memorial Hospital and then studied steroid biochemistry with Dr Seymour Lieberman at Columbia University. After his return to Southwestern Medical School, he rapidly earned a reputation as an astute clinician, a gifted teacher, and a brilliant investigator. He was one of a relatively small group of clinical scientists whose career was spent wedding basic sciences with obstetrics, gynecology, and human reproduction. His earliest scientific discoveries included elucidation of the origin and interconversion of gonadal and adrenal steroid hormones in children, women, and men.