March 25, 1998

HIV Treatment StrategiesPlanning for the Long Term

Author Affiliations

From the Division of International Medicine and Infectious Diseases, New York Hospital–Cornell Medical Center, New York, NY.

JAMA. 1998;279(12):957-959. doi:10.1001/jama.279.12.957

Significant progress has been made in the development of effective antiretroviral drug regimens for the treatment of human immunodeficiency virus (HIV) disease. Combinations of antiretroviral agents have been shown to decrease HIV RNA levels to the limit of detection of current viral load assays in a majority of patients for periods of months to years. These profound reductions in viral load reflect significant decreases in viral replication and appear to limit the emergence of resistant viral phenotypes, thereby promoting durable antiretroviral responses.

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