Edited by Brian P. Pace, MA, Assistant Editor.
The pathologic etiology of migraine has been long enough the subject
of speculation, but we are still in the phase of conjecture or at least theory;
our positive acquisitions of knowledge as to the essential pathologic process
are so far practically nothing. The notion that it is a vasomotor neurosis
has been largely abandoned, and neurologists at the present time are inclined
to class it with epilepsy as a fulgurant cortical neurosis, a symptom of cortical
instability associated, it may be, with some conditions of morbid metabolism,
such as the uric acid or arthritic diatheses. . . .
MIGRAINE AND EPILEPSY.. JAMA. 1998;279(14):1126J. doi:10.1001/jama.279.14.1126