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The Cover
November 11, 1998

Fasciculus Medicinae

JAMA. 1998;280(18):1552. doi:10.1001/jama.280.18.1552

Printed books were rare in the 15th century. Even rarer were printed books with illustrations. And, until 1491, even though a number of medical books were already in print, none had ever been illustrated. Thus, when the brothers de Gregorii printed Johannes de Ketham's Fasciculus Medicinae in Venice that year, it was a banner event. Not only was the Fasciculus Medicinae the first illustrated medical book printed, it was among the most beautiful of any of the so-called graphic incunabula, the term given to illustrated books printed prior to 1501.

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