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Health Agencies Update
June 25, 2014

Use of Immunotherapy for Gastrointestinal Cancers

Author Affiliations

Copyright American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.

JAMA. 2014;311(24):2473. doi:10.1001/jama.2014.7360

Evidence from a case study of a single patient suggests that an immunotherapy technique may help shrink epithelial cell cancers. The work was funded by the National Cancer Institute.

Malignancies that arise in epithelial cells, such as gastrointestinal cancers, lung cancer, and breast cancer, account for about 90% of US cancer deaths, according to the study’s authors. Using an immunotherapy strategy that has proven effective in treating melanoma, researchers helped boost a patient’s immune response by treating her with T cells targeting mutations in her tumor (Tran E et al. Science. 2014;344[6184]:641-645).

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