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Comment & Response
July 2, 2014

Kidney Donation and Risk of ESRD

Author Affiliations
  • 1Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts
  • 2Transplant Center, Beth Israel Deaconess Medical Center, Boston, Massachusetts
JAMA. 2014;312(1):92. doi:10.1001/jama.2014.5521

To the Editor Dr Muzaale and colleagues1 matched all US kidney donors from 1994 to 2011 with a cohort of selected participants from the Third National Health and Nutrition Examination Survey (NHANES III) and found an increased cumulative incidence and lifetime risk of end-stage renal disease (ESRD) among the donors. The Editorial by Drs Gill and Tonelli2 highlighted several methodological factors that may have biased the findings in the direction of finding increased risk to donors, and we identify an additional factor.

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