[Skip to Content]
[Skip to Content Landing]
Views 10,845
Citations 0
JAMA Diagnostic Test Interpretation
July 9, 2014

Aldosterone-Renin Ratio in the Assessment of Primary Aldosteronism

Author Affiliations
  • 1Department of Internal Medicine, University of Kentucky, Lexington
  • 2Department of Internal Medicine, University of Nebraska, Omaha
JAMA. 2014;312(2):184-185. doi:10.1001/jama.2014.64

A middle-aged patient with diabetes and hypertension presented to his primary care physician for regular health assessment. His blood pressure was 183/116 mm Hg despite taking lisinopril (40 mg/d) and verapamil (180 mg/d). He had previously taken hydrochlorothiazide, which was discontinued due to hypokalemia approximately 1 month ago, as well as atenolol, which was stopped 2 months earlier. As part of the workup for secondary hypertension, plasma aldosterone concentration and plasma renin activity were measured (Table 1).

First Page Preview View Large
First page PDF preview
First page PDF preview