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JAMA Revisited
July 23/30, 2014

Screening Test for HTLV-III (AIDS Agent) AntibodiesSpecificity, Sensitivity, and Applications

Author Affiliations

January 11, 1985


JAMA. 1985;253( (2) ):221-- 225.PubMed

JAMA. 2014;312(4):442. doi:10.1001/jama.2013.279636

The third member of the family of human T-cell leukemia (lymphotropic) retroviruses, HTLV-III, has emerged as the likely etiologic agent of the acquired immunodeficiency syndrome (AIDS).1,2 There is a recognized need for a serological assay for HTLV-III that could be used for epidemiologic studies and screening of defined populations. Ideally, such a test would be reproducible, specific, sensitive,3 relatively inexpensive, timely, and noninvasive.…

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