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Screening for liver cancer may not reduce the risk of liver cancer–related death, according to a systematic review assessing studies of screening tests for liver cancer in high-risk individuals (those with liver cirrhosis or chronic hepatitis B infection).
Overall, the evidence is of low quality and offers no proof that screening these individuals provides any advantage in extending life or in decreasing mortality from the disease, the researchers said. None of the studies examined the harms of screening or overdiagnosis or finding very slow-growing tumors that never would have otherwise caused problems in a patient’s lifetime.
News From JAMA’s Daily News Site. JAMA. 2014;312(5):476. doi:10.1001/jama.2014.9186