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Clinical Trials Update
August 27, 2014

MI Survivors Who Quit Using Snuff Add Years to Their Lives

JAMA. 2014;312(8):778. doi:10.1001/jama.2014.10951

Individuals younger than 75 years who quit using oral moist snuff after a myocardial infarction (MI) nearly halved their mortality risk compared with those who continued its use after MI, according to a prospective cohort study of 2474 Swedish MI survivors (Arefalk G et al. Circulation. 2014;130[4]:325-332). In Sweden, 20% of men and 3% of women are daily users of snus, the Swedish form of snuff, which has similar levels of nicotine to US moist snuff brands.

During a mean follow-up of 2.1 years, the mortality rate after MI was 9.7 per 1000 person-years at risk for snus quitters and 18.7 per 1000 person-years at risk for those who continued to use snuff. The 50% lower mortality rate in snus quitters after MI is similar to the lower mortality rate in individuals who quit smoking after MI. “These observations suggest that the use of snus post-MI should be discouraged,” wrote the researchers.

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