In Reply Accurate estimation of the prevalence of childhood diabetes is challenging. Dr Demmer and colleagues raised 2 issues: undiagnosed diabetes and geographic representativeness.
The SEARCH study design cannot estimate undiagnosed diabetes and, while not an issue for type 1 diabetes, the SEARCH study design will underestimate total type 2 diabetes burden. We expect this underestimation to be small, based on the only 2 available studies, which were mentioned by Demmer and colleagues. Nevertheless, they represent the only studies of screening that confirmed undiagnosed type 2 diabetes in youth.
Dabelea D, Mayer-Davis EJ. Diabetes Prevalence Among Youth—Reply. JAMA. 2014;312(11):1153-1154. doi:10.1001/jama.2014.9620