In Reply Dr White and colleagues raise 4 issues. First, they are concerned about differential treatment effects according to disease severity given that half of our participants had moderate to severe hip osteoarthritis and that their experience shows that those with moderate to severe hip osteoarthritis do not respond as favorably to most conservative treatment. This is a possibility although an exploratory post hoc analysis of the data showed no significant differences in the amount of improvement in pain (P = .76) and function (P = .38) comparing disease severity subgroups with active and sham treatment.
Bennell K, Abbott JH. Physical Therapy and Hip Osteoarthritis—Reply. JAMA. 2014;312(12):1257-1258. doi:10.1001/jama.2014.9826