Potent regimens involving combinations of antiretroviral drugs have substantially reduced the incidence of opportunistic infections (OI) and extended life in people infected with HIV—leading to new questions about prophylaxis against specific OIs in such patients. Now an international group of AIDS experts convened by the US Public Health Service (USPHS) and the Infectious Disease Society of America (IDSA) has drafted new recommendations that reflect important new data that have emerged since 1997, when the USPHS/ISDA guidelines on OI prophylaxis were last revised.
Stephenson J. HIV/AIDS Guidelines. JAMA. 1999;282(3):226. doi:10.1001/jama.282.3.226