Fever is a common medical complication for many types of critical neurologic illnesses, including acute ischemic stroke, intracerebral hemorrhage, subarachnoid hemorrhage, and brain trauma. In prospective observational studies, fever has been found in nearly 75% of patients.1 Fever is a form of secondary injury and independently worsens neurologic outcome and increases the mortality in neurologic patients.1 Hence, fever is a therapeutic target that needs to be identified, understood, and treated.
Vespa PM. Fever in Critical Neurologic Illness. JAMA. 2014;312(14):1456-1457. doi:10.1001/jama.2014.12492