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Comment & Response
October 15, 2014

Benefits and Risks Associated With Thrombolysis for Pulmonary Embolism

Author Affiliations
  • 1Department of Internal Medicine, Azienda Ospedaliera di Cosenza, Cosenza, Italy
JAMA. 2014;312(15):1589. doi:10.1001/jama.2014.10786

To the Editor The optimal treatment of intermediate-risk patients with pulmonary embolism (hemodynamically stable patients with right ventricular dysfunction or increased cardiac biomarkers) is an important issue, and the meta-analysis by Dr Chatterjee and colleagues1 showed a reduction in mortality with the use of thrombolysis compared with anticoagulation in this group of patients. However, in my opinion caution is due in interpreting these results.

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