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Comment & Response
October NaN, 2014

Insulin vs Sulfonylureas for Second-Line Diabetes Treatment—Reply

Author Affiliations
  • 1Department of Medicine, University of Alabama, Birmingham
JAMA. 2014;312(16):1695-1696. doi:10.1001/jama.2014.11129

In Reply Dr Roumie and colleagues have clarified the interpretation of their analysis of unmeasured confounder imbalance in their study.1 Because their analysis reported absolute differences, as they point out in their letter, the prevalence of unmeasured confounders would need to be quite high in the insulin-treated group with little or no prevalence in the sulfonylurea-treated group to explain the findings of their study.

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