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From the Food and Drug Administration
October 6, 1999

Warning on Dietary Supplements

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Copyright 1999 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.1999American Medical Association

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JAMA. 1999;282(13):1218. doi:10.1001/jama.282.13.1218

The FDA has issued a warning about a group of products—sold as "party drugs" or dietary supplements for body building, weight loss, and sleep inducement—that pose a significant hazard to public health. The products, sold under such names as GHB, Renewtrient, Revivarant, Blue Nitro, Firewater, and Serenity, are chemically related to γ-butyrolactone (GBL), γ-hydroxybutyric acid (GHB), and 1,4 butanediol (BD). They can cause dangerously low respiratory rates, unconsciousness or coma, vomiting, seizures, bradycardia, and death.

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