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Medical News & Perspectives
October 27, 1999

Knockout Science: Chubby Mice Provide New Insights Into Obesity

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JAMA. 1999;282(16):1507-1508. doi:10.1001/jama.282.16.1507

Chubby mice with blond bellies and an artfully disabled gene are giving scientists new insights into factors that can contribute to obesity, according to a new study reported last month (Nat Med. 1999;5:1066-1070).

Besides shedding light on obesity, the rotund rodents are also shedding weight when treated with a drug that helps compensate for the genetic defect, a finding with potential implications for treating obesity in humans.

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