Interest in antioxidants such as vitamins C and E, selenium, and carotenoids has soared in recent years, in large part due to epidemiological studies suggesting that foods rich in these substances reduce the risk of chronic diseases. But a new report from the Institute of Medicine warns that people who ingest these substances in the form of dietary supplements should be aware that benefits are unproven and large doses can harm rather than help.
Stephenson J. Easy on the Antioxidants. JAMA. 2000;283(19):2514. doi:10.1001/jama.283.19.2514