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November 8, 2000

Noninvasive Positive Pressure Ventilation in Acute Respiratory Failure

Author Affiliations

Author Affiliation: Royal Columbian Hospital, New Westminster, British Columbia.

JAMA. 2000;284(18):2376-2378. doi:10.1001/jama.284.18.2376

Almost 2 decades after the introduction of noninvasive positive pressure ventilation (NPPV), researchers continue to try to catch up with the necessary evaluation to answer key clinical questions about this intervention. For instance, should NPPV be used in patients with acute respiratory failure? If so, do some patients benefit more than others? Can NPPV ever cause harm in this setting? While the puzzle is not complete, each study contributes a new piece that provides a glimpse of the big picture. Two studies, in this issue of the THE JOURNAL1,2 provide important data on the effectiveness of NPPV in acute respiratory failure.

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