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Clinical Crossroads Update
November 22/29, 2000

An 80-Year-Old Man With Memory Loss, 1 Year Later

Author Affiliations

From the Division of General Medicine and Primary Care, Beth Israel Deaconess Medical Center, 330 Brookline Ave, LY318, Boston, MA 02215.

JAMA. 2000;284(20):2639. doi:10.1001/jama.284.20.2639

In September 1999, at Medicine Grand Rounds, Eric B. Larson, MD, MPH, addressed the evaluation and treatment of an 80-year-old retired teacher who had experienced slowly progressive memory loss for 7 years.1 He was the principal caregiver for his wife, disabled by a chronic, degenerative illness, and a severe stroke. On evaluation, Mr J exhibited variable abnormalities of retention and recall, appeared depressed, and the question of early Alzheimer disease was raised by his family and primary physician. Dr Larson discussed the epidemiology and spectrum of diseases associated with early dementia and outlined a strategy for the evaluation and treatment of such patients. We asked the patient, his son, and his primary care physician to comment on the year that followed the rounds.

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