From the Division of General Medicine and Primary Care, Beth Israel Deaconess Medical Center, 330 Brookline Ave, LY318, Boston, MA 02215.
In September 1999, at Medicine Grand Rounds, Eric B. Larson, MD, MPH,
addressed the evaluation and treatment of an 80-year-old retired teacher who
had experienced slowly progressive memory loss for 7 years.1
He was the principal caregiver for his wife, disabled by a chronic, degenerative
illness, and a severe stroke. On evaluation, Mr J exhibited variable abnormalities
of retention and recall, appeared depressed, and the question of early Alzheimer
disease was raised by his family and primary physician. Dr Larson discussed
the epidemiology and spectrum of diseases associated with early dementia and
outlined a strategy for the evaluation and treatment of such patients. We
asked the patient, his son, and his primary care physician to comment on the
year that followed the rounds.
Delbanco T, Hartman EE. An 80-Year-Old Man With Memory Loss, 1 Year Later. JAMA. 2000;284(20):2639. doi:10.1001/jama.284.20.2639