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January 3, 2001

Chlamydia and Cervical CancerA Real Association?

Author Affiliations

Author Affiliation: Division of Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, Md.

JAMA. 2001;285(1):81-83. doi:10.1001/jama.285.1.81

Worldwide, cervical cancer is among the 3 most prevalent malignancies in women, with more than 400 000 cases reported in 1998, of which 12 800 were in the United States.1 The causal relationship between subtypes of human papillomavirus (HPV) and cervical cancer has been firmly established. The epidemiological data are compelling and consistent, most recently from nested case-control studies in Scandinavia that demonstrated HPV in specimens collected before incident cervical intraepithelial neoplasia (CIN).2,3

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