Author Affiliation: Columbia School of Public Health, New York, NY.
In this issue of THE JOURNAL, Frank and colleagues1
present a systematic review of studies assessing possible relationships between
maternal cocaine use during pregnancy and several childhood outcomes. The
authors are thoughtful and rigorous in their approach and carefully evaluate
the physiological plausibility of the outcomes under question and the methodological
strengths and constraints of the studies reviewed. They considered 36 studies
worthy of review; these reported on 17 prospectively recruited cohorts with
examiners blinded to cocaine exposure status.
Chavkin W. Cocaine and Pregnancy—Time to Look at the Evidence. JAMA. 2001;285(12):1626-1628. doi:10.1001/jama.285.12.1626