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From the Food and Drug Administration
April 4, 2001

New Formulation of Tripedia

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Copyright 2001 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.2001American Medical Association

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JAMA. 2001;285(13):1696. doi:10.1001/jama.285.13.1696

The FDA has approved a new, preservative-free formulation for a diphtheria and tetanus toxoids and acellular pertussis (DTaP) vaccine (Tripedia, Aventis Pasteur, Swiftwater, Pa). The reformulated product contains less than 0.3 µg mercury per dose (as thimerosal), which is less than 5% of the amount of thimerosal in the original version that the FDA approved in 1992.

Although no harmful effects have been reported from thimerosal in vaccines when used at the recommended dosages, federal public health agencies, the American Academy of Pediatrics, and vaccine manufacturers have agreed to reduce or eliminate its use in vaccines to protect children against the potential cumulative health risks of mercury.

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