In Reply The synopsis of our Cochrane review of exercise for depression described the key results, the summary estimates of standardized mean differences, of the larger review. These results underwent rigorous peer review prior to publication in the Cochrane Library. We are confident about the validity and interpretation of the overall effect size, which was moderate and equivalent to a difference in the Beck Depression Inventory (BDI) of about 5 points between exercise and control.
Cooney GM, Dwan K, Mead G. Exercise to Combat Depression—Reply. JAMA. 2014;312(20):2167. doi:10.1001/jama.2014.14340